The pair have been edging closer and closer to the door this season, having barely featured for the first team, and have both been linked with moves away in summer.
However, they received the clearest sign yet that they are not wanted at the club, as neither player was involved in a photo shoot for the side's new kit, as reported by the 'Daily Mail'.
Furthermore, neither of the two have been included in the promotion of United's summer tour to the USA, which will take place after the World Cup.
Blind and Darmian have both made just three starts in the league this season, and it seems neither of them are included in Jose Mourinho's plan's next season. Darmian has been heavily linked with a move to the Serie A, with Juventus touted as a likely destination, with Blind also rumoured to be on his way to Italy.
Mourinho is expected to clear a good number of players out this summer, and Timothy Fosu-Mensah and Axel Tuanzebe are two other players reportedly on their way out, as well as Marouane Fellaini.