Arsene Wenger and his players were left incensed by Mike Dean's decision to award West Brom a late penalty as the Gunners came away from The Hawthorns with a 1-1 draw. At the Emirates, they will look to bounce back with a win over the Blues.
Chelsea are seven points above Arsenal on the table and, having dropped just two points in the festive period so far, a win on Wednesday could see them leapfrog Manchester United into second. Chelsea are have won more away games at the Emirates than any other team.
Mesut Ozil and Laurent Koscielny could return for Arsenal while Sead Kolasinac will be out for two weeks with an ankle problem. Aaron Ramsey, Olivier Giroud (both hamstring) and Nacho Monreal (ankle) all remain sidelined.
David Luiz (knee) and Charly Musonda (groin) will not feature for the visitors, who have no fresh injuries.
Recent form:
Predicted lineups:
Arsenal: Cech, Chambers, Mustafi, Mertesacker, Bellerin, Wilshere, Xhaka, Maitland-Niles, Iwobi, Sanchez, Lacazette
Chelsea: Courtois, Azpiliceuta, Christensen, Cahill, Moses, Bakayoko, Kante, Fabregas, Alonso, Hazard, Morata