A much-awaited clash in the Premier League. The two sides of Manchester are set to battle it out with the outcome potentially deciding the Premier League before Christmas.
"Football is unpredictable," Mourinho said. "As a manager, I can try to define a game plan and work a direction but you don't know what can happen. There are so many things that are out of my control that can totally transform the direction of the game."
"For me, it's one more big match against one of the best teams in the country. We are a better team than last year. I think Man City is also better than last season."
Manchester City remain unbeaten in the league and a win could take them 11 points clear at the top of the table, but Guardiola played down the decisive nature of the clash.
"I am a manager to play these kinds of games on the biggest stages. That's why we are here," Pep Guardiola said. "I will enjoy it, definitely. I am looking forward to arriving and playing. I love to be there, working out what we can do to beat them. After, we shake hands."
"Winning, drawing or losing, we are not going to win or lose the Premier League. It's an important game because you can win points but it's the same for them. All we are thinking is how to play well and win the game."
Ibrahimovic, Jones and Matic are available for United, although midfielder Marouane Fellaini will be assessed ahead of the game. Paul Pogba is serving the first of a three-match ban on Sunday after he was sent off in last weekend's win over Arsenal. Michael Carrick and Eric Bailly are also sidelined.
David Silva is fit for the Old Trafford trip after overcoming a knock but captain Vincent Kompany is doubtful with an unspecified problem. Fabian Delph has recovered from a sickness bug but John Stones (hamstring) and Benjamin Mendy (knee) are still out.
Recent form:
Possible lineups:
Manchester United: De Gea; Lindelof, Smalling, Rojo; Valencia, Matic, Herrera, Young; Lingard, Martial, Lukaku
Manchester City: Ederson; Walker, Otamendi, Kompany, Delph; De Bruyne, Fernandinho, Silva, Sterling, Aguero, Sane